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Chromosome painting without competitor DNA

✍ Scribed by Johannes Wienberg; Emma Adamski; Fengtang Yang; Stephan Müller; Malcolm A. Ferguson-Smith


Book ID
114392976
Publisher
Elsevier
Year
1997
Weight
147 KB
Volume
2
Category
Article
ISSN
1366-2120

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Topoisomerase II has been suggested to play a major role in chromosome organization based on its DNA decatenating activity and its ability to mediate direct binding interactions between DNA and nuclear matrix. However, this latter point remains controversial. Here we address the question of whether