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Chromosome losses in tumorigenic revertants of EJ/ras-expressing somatic cell hybrids

✍ Scribed by Carol I. Pratt; Shi-Qi Wu; Manju Bhattacharya; Chinghai Kao; Kennedy W. Gilchrist; Catherine A. Reznikoff


Book ID
119105467
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
1016 KB
Volume
59
Category
Article
ISSN
0165-4608

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The transcriptional activity of ten cellular oncogenes was analyzed in somatic cell hybrids that had been obtained after fusion of tumorigenic Chinese hamster cells and normal mouse fibroblasts. The hybrids showed either the tumorigenic or the nontumorigenic phenotype (suppression of tumorigenicity)