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Chromosome instability in cell lineages of amniocyte clones morphologically transformed by Simian virus 40

✍ Scribed by Kirsten H. Walen

Book ID
119103541
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
622 KB
Volume
25
Category
Article
ISSN
0165-4608

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Malignant transformation of simian virus
Malignant transformation of simian virus 40–immortalized human milk epithelial cells by chemical carcinogenesis accompanied by loss of heterozygosity on chromosome 1 but not microsatellite instability
✍ Kiyoshi Sasaki; Nikolai Mironov; Aysim Yilmaz; Harald Lahm; Nikolas Odartchenko; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 103 KB πŸ‘ 2 views

Simian virus 40-immortalized human milk epithelial cells (HuMI) are anchorage dependent and nontumorigenic but can spontaneously progress to anchorage-independent and tumorigenic cells. To see whether HuMI cells can be transformed into anchorage-independent cells by chemical carcinogens, we treated