Chromosome abnormalities in benign prostatic hyperplasia
β Scribed by Magdy S. Aly; Paola Dal Cin; Herman Van Den Berghe; Wim Van De Voorde; Hein Van Poppel; Filip Ameye; Luc Baert
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 503 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1045-2257
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β¦ Synopsis
We combined conventional cytogenetic analysis and fluorescence in situ hybridization of short-term cultures of 28 samples from benign prostatic hyperplasia. Lou of the Y chromosome was the most common chromosome change, followed by trisomy 7.
Trisomy 7, however, may be unrelated to the origin of benign prostate hyperplasia, in which the only and not very specific change seems to be the loss of the Y chromosome. Genes Chrom Cancer 9:227-233 (1594).
cinomas, primary and metastatic tumors, as well as
π SIMILAR VOLUMES
BACKGROUND. Benign prostatic hyperplasia (BPH) is mainly a stromal process, showing an increased ratio of stromal to epithelial elements, a collagen type III downregulation, and a collagen types I and IV upregulation. Little is known about elastin gene expression in BPH tissues due to difficulties r