Chromosome abnormalities and p53 expression in a small cell carcinoma of the bladder
โ Scribed by Niels B. Atkin; Marion C. Baker; George D. Wilson
- Book ID
- 113253330
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 252 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0165-4608
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๐ SIMILAR VOLUMES
Small cell carcinomas (SCCs) represent a rare histological subtype of urinary bladder cancer. Little is known abut the genetic alterations in these tumours. To identify chromosomal aberrations that are typically present in SCC of the urinary bladder, ten tumours were analysed by comparative genomic
## Abstract Abnormalities of the __p53__ gene are frequently observed in human tumors, including urinary bladder carcinoma, suggesting that __p53__ plays an important role in human carcinogenesis. However, its role in rat bladder carcinogenesis is unclear. We investigated __p53__ gene mutations and