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Chromosome 7q21–22 and multiple sclerosis: evidence for a genetic susceptibility effect in vicinity to the protachykinin-1 gene

✍ Scribed by Koen Vandenbroeck; Pierre Fiten; Shirley Heggarty; An Goris; Eleonora Cocco; Stanley A. Hawkins; Colin A. Graham; Maria G. Marrosu; Ghislain Opdenakker


Book ID
114137578
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
219 KB
Volume
125
Category
Article
ISSN
0165-5728

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Pulver et al. [1994a] reported modest linkage evidence for a dominantly (D) inherited ''schizophrenia gene'' in the vicinity of IL2RB on chromosome 22q12, and Coon et al. [1994] adduced moderate evidence under a recessive (R) model. We report here a replication study to test the hypothesis that one