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Chromosome 3p alterations in pancreatic endocrine neoplasia

✍ Scribed by Eliana Amato; Stefano Barbi; Giorgio Malpeli; Samantha Bersani; Giuseppe Pelosi; Paola Capelli; Aldo Scarpa


Publisher
Springer
Year
2010
Tongue
English
Weight
136 KB
Volume
458
Category
Article
ISSN
1432-2307

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Pancreatic endocrine tumors occur sporadically and as part of the multiple endocrine neoplasia type 1 (MEN 1) and von Hippel-Lindau (VHL) syndromes. The MEN1 locus on 11q13 and a candidate tumor suppressor locus on 3p are known to be hemi-or homozygously mutated in a subset of these tumors. Chromoso

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