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Chromosome 22q11 deletions are not found in autistic patients identified using strict diagnostic criteria

✍ Scribed by Ogilvie, Caroline Mackie; Moore, Janette; Daker, Michael; Palferman, Sarah; Docherty, Zoe


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
5 KB
Volume
96
Category
Article
ISSN
0148-7299

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✦ Synopsis


A group of 103 subjects with a strict diagnosis of autism were tested for deletion of band q11.2 on the long arm of chromosome 22. No deletions were found, indicating that when a patient has been diagnosed with autism using strict and consistent criteria, in the absence of other indications, it is unlikely that this individual will have a 22q11 deletion. Testing for 22q11 deletions is therefore unlikely to be necessary in these patients.