✦ LIBER ✦

Chromosome 18 translocation (18;21) (p11.1;p11.1) associated with psychosis in one family

✍ Scribed by Smith, Angela B.; Peterson, Paula; Wieland, Judith; Moriarty, Timothy; DeLisi, Lynn E.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 436 KB
Volume: 67
Category: Article
ISSN: 0148-7299
DOI: 10.1002/(sici)1096-8628(19961122)67:6<560::aid-ajmg9>3.0.co;2-l

No coin nor oath required. For personal study only.

✦ Synopsis

In the course of recruiting families with 2 schizophrenic siblings for genome screening and linkage studios, a family was found with mental retardittion, schizophrenia, andor other related psychotic illnesses in individuals who also had an unbalanced or balanced translocation between chromosomes 21-18 [t(18;21) (pll.l;pll.l)]. The pericentric region of chi~omosome 18 has already been noted as a possible location of a gene for bipolar psychosis. The family described here provides further evidence that this region should be examined for a candidate psychosis gene.

📜 SIMILAR VOLUMES

De novo duplication of 18p11.21–18q12.1

De novo duplication of 18p11.21–18q12.1 in a female with anorectal malformation

✍ Charlotte Schramm; Markus Draaken; Enrika Bartels; Thomas M. Boemers; Eberhard S 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB 👁 1 views

Patient with rheumatoid arthritis and MC

Patient with rheumatoid arthritis and MCA/MR syndrome due to unbalanced der(18) transmission of a paternal translocation t(18;20)(p11.1;p11.1)

✍ Czakó, Márta ;Riegel, Mariluce ;Morava, Éva ;Schinzel, Albert ;Kosztolányi, Györ 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB 👁 2 views

## Abstract A girl with psychomotor retardation and a pattern of minor anomalies was found to have a slightly enlarged short arm of chromosome 18 by conventional GTG‐banded chromosome examination. The 18p + chromosome has also been found in the father. FISH studies using chromosome 18–and chromosom

Translocation t(5;11)(q13.1;p13) associa

Translocation t(5;11)(q13.1;p13) associated with familial isolated aniridia

✍ Pettenati, Mark J. ;Weaver, R. Grey ;Burton, Barbara K. 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

A father a n d daughter with isolated aniridia were observed to have a n apparently balanced, reciprocal translocation involving chromosomes 5 and 11 [t(5;ll)(ql3.l;pl3)1. No other clinical characteristics often associated with the deletion of llp13 were observed in this family. This finding, in ass

Chromosome 18 breakpoint in t(11;18)(q21

Chromosome 18 breakpoint in t(11;18)(q21;q21) translocation associated with MALT lymphoma is proximal to BCL2 and distal to DCC

✍ Archontoula Stoffel; Pulivarthi H. Rao; Diane C. Louie; Kenneth Krauter; David N 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB 👁 2 views

The t(11;18)(q21;q21) translocation has recently been identified as a recurring chromosomal abnormality in a subset of extranodal marginal zone B-cell lymphoma, a low-grade lymphoma of mucosa-associated lymphoid tissue (MALT). Neither the 11q21 nor the 18q21 breakpoints have been characterized by mo

Suggestive linkage of a chromosomal locu

Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families

✍ Lynn M. Evans; Hagop S. Akiskal; Tiffany A. Greenwood; Caroline M. Nievergelt; P 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB 👁 1 views

## Abstract Attempts to identify bipolar disorder (BP) genes have only enjoyed limited success. One potential cause for this problem is that the traditional categorical BP phenotypes currently used in genetic linkage studies are not the most informative, efficient, or biologically relevant. An alte

Pseudoarthrosis of the clavicle and copp

Pseudoarthrosis of the clavicle and copper beaten skull associated with chromosome 10p11.21p12.1 microdeletion

✍ Raveen Shahdadpuri; Bert de Vries; Rolph Pfundt; Nicole de Leeuw; William Reardo 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB