Chromosomal translocation t(14;18) in healthy individuals
✍ Scribed by Frank Schüler; Carsten Hirt; Gottfried Dölken
- Book ID
- 114340607
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 77 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1044-579X
No coin nor oath required. For personal study only.
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## Abstract The t(14;18) translocation is a common genetic aberration that can be seen as an early step in pathogenesis of follicular lymphoma (FL). The significance of low level circulating t(14;18)‐positive cells in healthy individuals as clonal lymphoma precursors or indicators of risk is still
## Abstract Chromosomal translocations (CTs) are hallmark mutations of hematopoietic malignancy that result in the deregulated expression of oncogenes or the generation of novel fusion genes. The polymerase chain reaction (PCR) can be used to detect illegitimate recombinations of genomic DNA sequen