Chromosomal sublocalization of the human p97 melanoma antigen
✍ Scribed by Michelle M. Beau; M. O. Diaz; G. D. Plowman; J. P. Brown; Janet D. Rowley
- Book ID
- 104707053
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 339 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0340-6717
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## Abstract The unlabelled antibody technique of Sternberger was used to study the localization in histological sections of human melanoma‐associated antigen p97, which is defined by a monoclonal antibody. The antigen was detected in 8 of 10 primary skin melanomas, in 6 of 7 metastatic melanomas an
## Abstract Conjugates (immunotoxins) comprising ricin A‐chain and monoclonal antibody 96.5, which is specific for human melanoma‐associated antigen p97, inhibited protein synthesis and colony formation of cultured human melanoma cells that expressed more than 80,000 molecules of p97 per cell. Cell