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Chromosomal radiosensitivity of breast cancer with a CHEK2 mutation

✍ Scribed by Ans Baeyens; Kathleen Claes; Petra Willems; Kim De Ruyck; Hubert Thierens; Anne Vral


Book ID
113512730
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
155 KB
Volume
163
Category
Article
ISSN
0165-4608

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## Abstract The 1100delC mutation of the cell cycle checkpoint kinase 2 (__CHEK2__) gene confers an increased risk for breast cancer, but the clinical impact of other __CHEK2__ gene variants remains unclear. We determined the frequency of two functionally relevant __CHEK2__ gene mutations, I157T an