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Chromosomal location and genetic mapping of the mismatch repair gene homologs MSH2 , MSH3 , and MSH6 in rye and wheat

✍ Scribed by Korzun, V; Börner, A; Siebert, R; Malyshev, S; Hilpert, M; Kunze, R; Puchta, H


Book ID
121380992
Publisher
NRC Research Press
Year
1999
Tongue
English
Weight
49 KB
Volume
42
Category
Article
ISSN
0831-2796

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## Abstract Epigenetic silencing of the O^6^‐methylguanine‐DNA methyltransferase (__MGMT__) gene promoter is associated with prolonged survival in glioblastoma patients treated with temozolomide (TMZ). We investigated whether glioblastoma recurrence is associated with changes in the promoter methyl