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Chromosomal integrity and DNA damage in freeze-dried spermatozoa

✍ Scribed by Hirokazu Kusakabe


Book ID
107660170
Publisher
Springer Japan
Year
2011
Tongue
English
Weight
393 KB
Volume
10
Category
Article
ISSN
1445-5781

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## Abstract ## Background PhiC31 integrase facilitates efficient integration of transgenes into human and mouse genomes and is considered for clinical gene therapy. However recent studies have shown that the enzyme can induce various chromosomal abnormalities in primary human embryonic cells and m