## BACKGROUND. A preoperative diagnosis of medullary carcinoma of the thyroid (MCT) allows for the investigation of associated multiple endocrine neoplasia/ pheochromocytoma, and definitive surgery without the need for frozen section. Criteria for cytodiagnosis are well known but variable patterns
β¦ LIBER β¦
Chromosomal instability in medullary carcinoma of the thyroid
β Scribed by Naguib A. Samaan; Sen Pathak; Mohammed F. Saad; Nelson G. Ordonez; Robert C. Hickey
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 491 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0364-2313
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Microsatellite instability (MSI) has been reported to occur in a wide variety of sporadic tumours, such as colorectal and gastric cancers. MSI positivity has been associated with a particular clinico-pathologic profile, including the presence of abundant lymphoid infiltration, poor differentiation a