Chromosomal imbalances detected by comparative genomic hybridisation in atypical teratoid/rhabdoid tumours
β Scribed by ChristianH. Rickert; Werner Paulus
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 232 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0256-7040
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Loss of heterozygosity and fluorescence in situ hybridization (FISH) studies have shown that deletions of 1p and 19q are highly prevalent in oligodendroglioma. However, these tumors have not been comprehensively screened for other alterations in chromosomal dosage. In this study, we use
Familial occurrence of gliomas, in the absence of well-defined hereditary multisystem disorders, is reported occasionally. We describe 17 families that have been afflicted with two or more gliomas but do not raise suspicion of other inheritable syndromes. The families were identified among 369 conse
## Abstract The genetic hallmark of retinoblastoma is mutation or deletion of the __RB1__ gene, whereas other genetic alterations that are also required are largely unknown. To screen for genomic imbalances on a genomewide level, we studied a series of 17 primary retinoblastomas by matrixβbased com