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Chromosomal imbalances associated with acquired resistance to fluoropyrimidines in human colorectal cancer cells

✍ Scribed by S Hidaka; T Yasutake; M Fukushima; H Yano; M Haseba; T Tsuji; T Sawai; H Yamaguchi; T Nakagoe; H Ayabe; Y Tagawa

Book ID
117659974
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
226 KB
Volume
39
Category
Article
ISSN
0959-8049

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## Abstract Therapy resistance is the major obstacle to advances in successful cancer treatment. To characterize chromosomal alterations associated with different types of acquired MDR and thermoresistance, we applied CGH to compare a unique panel of human gastric carcinoma cells consisting of the