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Chromosomal fragile sites in normal kidney cells and susceptibility to renal cell carcinoma

✍ Scribed by G Ott; B Roß; B Janssen; L Füzesi


Book ID
119105197
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
45 KB
Volume
52
Category
Article
ISSN
0165-4608

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It has been suggested that fragile sites on human chromosomes predispose to specific rearrangements seen in cancer. Renal cell carcinoma is characterised by recurrent aberrations of chromosome 3p and frequent rearrangements of chromosome 5q. To investigate whether there might be an association betwe