## Abstract Penile carcinomas are frequently associated with high risk human papillomavirus (HPV) types. Because little is known about the molecular biology of this association, we investigated three properties of HPV genomes in penile carcinomas from Brazilian patients: (__i__) HPV DNA methylation
Chromosomal DNA variation, genomic constraints and recombination inLathyrus
β Scribed by R. K. J. Narayan; F. K. McIntyre
- Publisher
- Springer Netherlands
- Year
- 1989
- Tongue
- English
- Weight
- 482 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0016-6707
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β¦ Synopsis
There is approximately a doubling of the total nuclear DNA between the 8 Lathyrus species and there are significant differences in the amounts of DNA in euchromatin and heterochromatin. Between the 8 species chiasma frequency and total nuclear DNA are not correlated but within complements it is positively correlated with the amount of DNA in the chromosomes. There is no significant correlation between chiasma frequency and euchromatin DNA nor between chiasma frequency and heterochromatin DNA among species, but among chromosomes, as with total DNA, it is positively correlated with euchromatin DNA and heterochromatin DNA. Results show that despite the large differences in DNA amounts between species there are genomic constraints underlying the frequency and distribution of chiasmata in the chromosome complements.
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