Chromosomal damage in sperm of patients surviving Hodgkin's disease following MOPP (nitrogen mustard, vincristine, procarbazine, and prednisone) therapy with and without radiotherapy
β Scribed by B. F. Brandriff; M. L. Meistrich; L. A. Gordon; A. V. Carrano; J. C. Liang
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 607 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0340-6717
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π SIMILAR VOLUMES
Since the introduction of mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) chemotherapy, children with Hodgkin's disease (HD) have been treated with chemotherapy alone. The occurrence of side effects related to irradiation (especially secondary solid tumors) is less likely to occur.
## Abstract Sixty patients with nonβHodgkin's lymphomas were treated with a cyclophosphamide, vincristine, and prednisone (CVP) induction regimen, either alone (stage IV) or in combination with radiotherapy (stages I, II, III). The response rates for lymphocytic and histocytic lymphomas were 82 an