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Chromosomal copy number changes of locally advanced rectal cancers treated with preoperative chemoradiotherapy

โœ Scribed by Marian Grade; Jochen Gaedcke; Danny Wangsa; Sudhir Varma; Jaje Beckmann; Torsten Liersch; Clemens Hess; Heinz Becker; Michael J. Difilippantonio; Thomas Ried; B. Michael Ghadimi


Book ID
113513549
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
508 KB
Volume
193
Category
Article
ISSN
0165-4608

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โœ Zhenbin Chen; Zheng Liu; Wenyan Li; Kun Qu; Xutao Deng; Madhulika G. Varma; Ales ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 939 KB

## Abstract Rectal cancer response to chemoradiation (CRT) varies from no response to a pathologic complete response (pCR). Identifying predictive biomarkers of response would therefore be useful. We assessed whether chromosomal copy number alterations (CNAs) can assist in predicting pCR. Pretreatm