Chromosomal assignment in mouse of matrix Gla protein and bone Gla protein genes
β Scribed by Johnson, Teresa L.; Sakaguchi, Alan Y.; Lalley, Peter A.; Leach, Robin J.
- Book ID
- 123100843
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 571 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0888-7543
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Methods. The immunoreactivity of bone GLA protein (BGP) in primary bone tumors, including osteosarcoma, chondrosarcoma, malignant fibrous histiocytoma of bone (MFH), and giant cell tumor of bone (GCT), was investigated with anti-BGP rabbit serum and peroxidase-antiperoxidase complex. As to intracel
Matrix Gla protein (MGP), is a vitamin-K-dependent protein which is synthesized in a variety of tissues such as lung, heart, kidney, cartilage and bone. The function of MGP in these tissues is unclear. We have previously reported elevated MGP mRNA levels in a breast-cancer cell line, 600PE1, as comp