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Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases

✍ Scribed by Smadja, N-V; Fruchart, C; Isnard, F; Louvet, C; Dutel, J-L; Cheron, N; Grange, M-J; Monconduit, M; Bastard, C

Book ID: 110053864
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 105 KB
Volume: 12
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2401041

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## Abstract Multiple myeloma (MM) is a malignant plasma cell disorder characterized by complex karyotypes and chromosome 1 instability at the cytogenetic level. Chromosome 1 instability generally involves partial duplications, whole‐arm translocations, or jumping translocations of 1q, identified by