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Chromosomal aberrations induced in human cultured cells by liposome-encapsulated deoxyribonuclease I

โœ Scribed by F. Nuzzo; F. Sala; O. Biondi; A. Casati; G. Osorio-Sanabria; B. Cestaro; G. Della Valle; L. De Carli


Book ID
113193096
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
582 KB
Volume
177
Category
Article
ISSN
0027-5107

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Non random distribution of lesions induc
โœ Fiorella Nuzzo; Alessandra Casati; Elena Raimondi ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 494 KB

We studied the action of deoxyribonuclease I on human lymphocytes in order to determine the localization of the DNAase induced aberrations. Our results indicate a non-random distribution of the lesions on chromosome regions which may reflect a differential pattern of sensitivity to the enzyme. Furth