Chromogranin A, a significant prognostic factor in small cell lung cancer
✍ Scribed by Drivsholm, L; Paloheimo, L I; Østerlind, K
- Book ID
- 110002525
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 65 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0007-0920
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Increased production of immunosuppressive interleukin-10 (IL-10) by non-small cell lung cancer (NSCLC) and increased serum IL-10 concentrations in NSCLC-patients have recently been correlated to reduced survival. We earlier demonstrated suppression of IL-2 secretion in whole blood cell cultures of N
## Abstract ## BACKGROUND. Increased levels of chromogranin A (CgA), a protein secreted by many neuroendocrine cells, have been detected in sera of patients with neuroendocrine tumors or renal, hepatic, or heart failure. In patients with heart failure, serum CgA correlates with tumor necrosis fact