โ Scribed by Thomas F. Mancuso
No coin nor oath required. For personal study only.
A continuation of the findings in a study of workers hired in 1931-1937 in a chromate plant, directed at the evaluation of the carcinogenic risk of insoluble, soluble, and total chromium. Chemical analyses of tissues of autopsies, identified by age at hire, cumulative exposure to insoluble, soluble, and total chromium and interval since last exposure are cited for three lung cancer cases. Histological identification of insoluble chromium was demonstrated. Marked deposition and retention of concentrations of chromium was noted 18.0 years since last exposure. In one case with cumulative exposure to insoluble chromium of 10.74 mg versus 0.63 mg for soluble chromium and histological demonstration of insoluble chromium, chrysotile was also identified.
๐ SIMILAR VOLUMES
Successive cohorts by year of hire at the same chromate plant (1931-1932, 1933-1934, 1935-1937) and the combined cohort (1931)(1932)(1933)(1934)(1935)(1936)(1937) of 332 employees were followed through 1993. A total of 283 deaths (85%) of the total cohort were identified. In the combined cohort (193