Indirect resolution of baclofen enantiom
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Ravi Bhushan; Virender Kumar
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Article
📅
2008
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John Wiley and Sons
🌐
English
⚖ 120 KB
👁 2 views
A high-performance liquid chromatographic (HPLC) method was developed for chiral assay of baclofen enantiomers in pharmaceutical formulations using an indirect approach. Baclofen enantiomers were derivatized with Marfey's reagent (FDNP-L-Ala-NH 2 ) and its structural variants FDNP-L-Phe-NH 2 , FDNP-