✦ LIBER ✦
Chromatographic isolation and estimation of zanthoxylol: An antisickling agent from the roots of Zanthoxylum species
✍ Scribed by A.A. Elujoba; L. Nagels
- Book ID
- 103910723
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 409 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0731-7085
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✦ Synopsis
The roots-of four species of Zanfhoxylum were examined for the presence of zanthoxylol (2-dimethylallyl-4-(3-hydroxy-propyl)phenol) but only 2. zanthoxyloides was found to contain this substance. Purification was effected using Sephadex ionexchange resins; isolation and quantification were performed on reversed-phase HPLC columns. The identity was confirmed by UV, IR, NMR, GC and MS analysis. The zanthoxylol content was calculated as p-hydroxybenzoic acid. The possible chemotaxonomic value of the zanthoxylol content in Zanthoxylum species is speculated.