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Chromatin structural elements and chromosomal translocations in leukemia

โœ Scribed by Yanming Zhang; Janet D. Rowley

Book ID
116410591
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
474 KB
Volume
5
Category
Article
ISSN
1568-7864

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## Abstract Chromosomal translocations (CTs) are hallmark mutations of hematopoietic malignancy that result in the deregulated expression of oncogenes or the generation of novel fusion genes. The polymerase chain reaction (PCR) can be used to detect illegitimate recombinations of genomic DNA sequen