Chromatin repositioning activity and transcription machinery are both recruited by Ace1p in yeast CUP1 activation

Both Sp1 and Sp3 are responsible for p21

Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells

✍ Hengyi Xiao; Tadao Hasegawa; Ken-ichi Isobe 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB

Histone deacetylase inhibitor-induced expression of p21 WAF1 is p53 independent. In the present study, we provide evidence that trichostatin A (TSA), a specific inhibitor of histone deacetylase, can elevate H3 and H4 acetylation and p21 WAF1 expression in NIH3T3 cells at first. To identify the trans