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Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

✍ Scribed by Archer, Trevor K.; Fryer, Christy J.

Book ID
109728217
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
302 KB
Volume
393
Category
Article
ISSN
0028-0836

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## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or