Histone modifying enzymes and cancer: Go
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Ke Zhang; Sharon Y.R. Dent
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Article
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2005
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John Wiley and Sons
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English
โ 211 KB
## Abstract Mutations in the molecular pathways that regulate cell proliferation, differentiation, and cell death all contribute to cancer formation. Enzymes that covalently modify histones affect these pathways by controlling the dynamic remodeling of chromatin structure. This article reviews seve