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Chromatin modifier enzymes, the histone code and cancer

โœ Scribed by Helena Santos-Rosa; Carlos Caldas


Book ID
118435701
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
487 KB
Volume
41
Category
Article
ISSN
0959-8049

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โœ Ke Zhang; Sharon Y.R. Dent ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 211 KB

## Abstract Mutations in the molecular pathways that regulate cell proliferation, differentiation, and cell death all contribute to cancer formation. Enzymes that covalently modify histones affect these pathways by controlling the dynamic remodeling of chromatin structure. This article reviews seve