## Abstract Rearrangements of __MLL__ are regarded as primary oncogenic events in acute leukemia. We report the case of a patient with acute myeloid leukemia with a complex abnormal karyotype at diagnosis who showed a putative stem line with monosomy 5 and a rearrangement of chromosome 17 as the on
โฆ LIBER โฆ
Chromatin modifications as therapeutic targets in MLL-rearranged leukemia
โ Scribed by Aniruddha J. Deshpande; James Bradner; Scott A. Armstrong
- Book ID
- 119263104
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 752 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1471-4906
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Late-appearing MLL rearrangement arising
โ
David Rowe; Gareth J. Breese; Anne Lennard; Nick Bown
๐
Article
๐
2002
๐
John Wiley and Sons
๐
English
โ 537 KB
The Syk kinase as a therapeutic target i
โ
Efremov, Dimitar G; Laurenti, Luca
๐
Article
๐
2011
๐
Informa plc
๐
English
โ 658 KB
The Syk kinase as a therapeutic target i
โ
Efremov, Dimitar G; Laurenti, Luca
๐
Article
๐
2011
๐
Informa plc
๐
English
โ 658 KB
## Introduction: The b-cell receptor (bcr) delivers antigen-dependent and -independent signals that have been implicated in the pathogenesis of several common b-cell malignancies. agents that can efficiently block bcr signaling have recently been developed and are currently being evaluated as novel
NF-ฮบB as a therapeutic target in chronic
โ
Lopez-Guerra, Monica; Colomer, Dolors
๐
Article
๐
2010
๐
Informa plc
๐
English
โ 588 KB
Mcl-1 as a therapeutic target in acute m
โ
Bose, Prithviraj; Grant, Steven
๐
Article
๐
2013
๐
Elsevier
๐
English
โ 263 KB
Epigenetic modifications as potential th
โ
Kwa, Faith A.A.; Thrimawithana, Thilini R.
๐
Article
๐
2014
๐
Elsevier Science
๐
English
โ 402 KB