Chromatin configuration and transcriptional control in human and mouse oocytes
✍ Scribed by Faïçal Miyara; Carole Migne; Martine Dumont-Hassan; Alain Le Meur; Paul Cohen-Bacrie; François-Xavier Aubriot; Amélie Glissant; Catherine Nathan; Stéphane Douard; Alexandre Stanovici; Pascale Debey
- Book ID
- 111661864
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 532 KB
- Volume
- 64
- Category
- Article
- ISSN
- 1040-452X
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## Abstract Despite many years of investigation by numerous investigators, transcriptional regulatory control remains an intensely investigated and continuously evolving field of research. Transcriptional regulation is dependent not only on transcription factor activation and chromatin remodeling,
The microtubules and chromosomes of 180 human oocytes failing to fertilize after intracytoplasmic sperm injection were observed in order to establish how sperm chromatin and sperm astral microtubule configuration is related to the phases of oocyte cell cycle, and to find the defects in those structu