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CHONDROITINSULPHATURIA WITH $alpha;-L-IDURONIDASE DEFICIENCY

โœ Scribed by BABARIK, A


Book ID
123195299
Publisher
The Lancet
Year
1974
Tongue
English
Weight
249 KB
Volume
304
Category
Article
ISSN
0140-6736

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On DEAE cellulose column chromatography, alpha-L-iduronidase in cultured skin fibroblasts was resolved into two distinct components, forms A and B. They had similar Km values for 4-methylumbelliferyl-alpha-L-iduronide, but differed in pH optima and thermal stability. Form B was more heat-stable than