Cholinergic transmission in the dorsal hippocampus modulates trace but not delay fear conditioning
β Scribed by Min-Hee Pang; Nam-Soo Kim; Il-Hwan Kim; Hyun Kim; Hyun-Taek Kim; June-Seek Choi
- Book ID
- 116791902
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 1017 KB
- Volume
- 94
- Category
- Article
- ISSN
- 1074-7427
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## Abstract Hippocampal and amygdaloid neuroplasticity are important substrates for Pavlovian fear conditioning. The hippocampus has been implicated in trace fear conditioning. However, a systematic investigation of the significance of the trace interval has not yet been performed. Therefore, this
## Abstract The present study sought to determine whether postβtraining excitotoxic lesions of the dorsal hippocampus would disrupt retention of fear conditioned using a trace procedure. Rats were trained using one of six procedures. Forward trace conditioning consisted of 10 trials in which a 16βs