It is now 30 years since the beginning of intensive efforts to understand the neurotransmitter biochemistry of dementia as exemplified by Alzheimer's disease and such studies have led to the development of rational treatment strategies, which are continuing to benefit patients. However, as studies b
✦ LIBER ✦
Cholinergic Deficit and Response to Donepezil Therapy in Parkinsons Disease with Dementia
✍ Scribed by Hiraoka, Kotaro; Okamura, Nobuyuki; Funaki, Yoshihito; Hayashi, Akiko; Tashiro, Manabu; Hisanaga, Kinya; Fujii, Toshikatsu; Takeda, Atsushi; Yanai, Kazuhiko; Iwata, Ren; Mori, Etsuro
- Book ID
- 119985811
- Publisher
- S. Karger AG
- Year
- 2012
- Tongue
- English
- Weight
- 231 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0014-3022
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## Abstract ## Background Cholinesterase inhibitors with additional nicotinic activity, such as galantamine, may be useful in PD patients with dementia (PDD) since stimulation of nicotinic receptors may prevent the down‐regualation that is likely to accompany cholinesterase inhibition and facilita