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Cholinergic antiinflammatory pathway inhibition of tumor necrosis factor during ischemia reperfusion

โœ Scribed by Bernik, Thomas R.; Friedman, Steven G.; Ochani, Mahendar; DiRaimo, Robert; Susarla, Seenu; Czura, Christopher J.; Tracey, Kevin J.


Book ID
123167449
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
95 KB
Volume
36
Category
Article
ISSN
1097-6809

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Although hepatic ischemia-reperfusion (IR) injury is partially mediated by tumor necrosis factor-alpha (TNF), we recently found that low-dose TNF before IR is hepatoprotective. We examined the seemingly conflicting roles of TNF in mediating liver injury in a partial hepatic IR model using TNF gene k