Cholesteryl ester metabolism in tissue culture cells: II. Source of accumulated esterified cholesterol in Fu5AH rat hepatoma cells
β Scribed by G. H. Rothblat; L. Arbogast; D. Kritchevsky; M. Naftulin
- Book ID
- 112771241
- Publisher
- Springer-Verlag
- Year
- 1976
- Tongue
- English
- Weight
- 926 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0024-4201
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## Abstract Diethylumbelliferyl phosphate (UBP) has been shown to inhibit the neutral cholesteryl ester hydrolase activity responsible for hydrolysis of cellular lipid droplet cholesteryl ester (Harrison et al., 1990). The potential for (UBP) to inhibit uptake and hydrolysis of high density lipopro
Rat hepatoma cells (Fu5AHj were studied as a model for the net delivery of apoE-free high-density lipoprotein (HDL) cholesterol to a cell. Incubating cells with HDL results in 1) a decrease in both media-free cholesterol and cholesteryl ester concentration; 2) decreased cell sterol synthesis; and 3)