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Cholesterol storage and bile secretion in chorio-allantoic grafts of liver

✍ Scribed by Dalton, A. J.

Publisher
John Wiley and Sons
Year
1937
Tongue
English
Weight
434 KB
Volume
67
Category
Article
ISSN
0003-276X

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The liver plays a critical role in the metabolism of lipoprotein cholesterol and in controlling its elimination through the bile. Niemann-Pick type C 2 (NPC2), a cholesterol-binding protein, is key for normal intracellular trafficking of lipoprotein cholesterol, allowing its exit from the endolysoso