𝔖 Bobbio Scriptorium
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Cholesterol, oxidative stress, and Alzheimer’s disease: expanding the horizons of pathogenesis

✍ Scribed by Miguel A Pappolla; Mark A Smith; Tara Bryant-Thomas; Nicolas Bazan; Suzana Petanceska; George Perry; Leon J Thal; Mary Sano; Lorenzo M Refolo

Book ID
114275162
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
244 KB
Volume
33
Category
Article
ISSN
0891-5849

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Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mecha