The objective of this study was to evaluate the effects which hydroxypropylmethylcellulose (HPMC) may exert on oral drug absorption, in cases where this soluble fiber is administered to regulate blood lipid levels. Studies were conducted in vitro and in healthy female mongrel dogs using two differen
Cholesterol-lowering effect of plant sterols
β Scribed by Ingmar Wester
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 221 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1438-7697
No coin nor oath required. For personal study only.
β¦ Synopsis
Plant sterols (phytosterols) are a group of compounds structurally very similar to cholesterol (Fig. ). The main plant sterols, sitosterol and campesterol differ from the structure of cholesterol by an ethyl and a methyl group, respectively, at C-24 in the side chain. These small differences have a remarkable impact on the fate of those compounds in the digestive tract. The absorption of sitosterol, the most common plant sterol, is only 10% of the absorption of cholesterol, whereas campesterol shows somewhat higher absorption (Tab. 1). Saturation of sito-
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