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Cholesterol biosynthesis and lipid biochemistry in the scolex of echinococcus granulosus

✍ Scribed by George A. Digenis; Ralph E. Thorson; Arpine Konyalian

Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
529 KB
Volume
59
Category
Article
ISSN
0022-3549

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✦ Synopsis

When live scolices of Echinococcus grunulosus were incubated with labeled mevalonate in vitro, no radioactivity was incorporated into the parasites' cholesterol fraction. However, labeled cholesterol was recovered after a scolices' homogenate was incubated with 4-14C-cholesteryl acetate. It is suggested that the scolex of E. grunulosus is unable to biosynthesize cholesterol and that it obtains cholesterol in an esterified form from the host, which is subsequently hydrolyzed within the scolex to free cholesterol. The fatty acid content of E. granulosus was examined by gasliquid chromatography.

Keyphrases

Echinococcus granulosus scolices-cholesterol biosynthesis 0 Cholesterol biosynthesis-E. grunulosus scolices 0 Lipid biochemistry-E. grunulosus scolices 0 Hydrolytic activity, E. granulosus scolices4-14C-cholesteryl acetate 0 TLC-separation 0 GLC-identity Scintillometry-analysis

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