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Cholesterol as liquifier in phospholipid membranes studied by surface viscosity measurements of mixed monolayers

✍ Scribed by P. Joos


Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
288 KB
Volume
4
Category
Article
ISSN
0009-3084

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✦ Synopsis


The surface viscosity of cholesterol, distearoyl lecithin, oleoyl-stearoyl lecithin monolayers and mixed monolayers of cholesterol with both lecithins were measured. The presence of cholesterol causes the surface viscosity of the phospholipid monolayer to be reduced, so cholesterol acts as a liquifier. This liquifaction of the mixed monolayer is a pure physical phenomena and follows from the rate theory of Eyring.