Cholestatic hepatitis, acute acalculous cholecystitis, and hemolytic anemia: primary Epstein–Barr virus infection under azathioprine
✍ Scribed by Stefan Hagel; Tony Bruns; Marcus Kantowski; Peter Fix; Thomas Seidel; Andreas Stallmach
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 109 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1078-0998
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✦ Synopsis
The use of immunomodulators for the treatment of inflammatory bowel disease (IBD) is increasing. One of the most common adverse effects associated with this kind of therapy is infectious complications. In recent years, special attention has been paid to certain latent infections which in patients under immunomodulatory therapy can be reactivated or primarily acquired with a higher incidence compared to the immunocompetent. Here we describe a patient with ulcerative colitis (UC) diagnosed with infectious mononucleosis complicated by acute cholestatic hepatitis, acute acalculous cholecystitis (AAC), cold agglutinin-associated hemolytic anemia, and pleuropneumonia under immunosuppression with azathioprine.