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Choleragen stimulates steroidogenesis and adenylate cyclase in cells lacking functional hormone receptors

✍ Scribed by J. Wolff; G. Hope Cook


Book ID
115722737
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
417 KB
Volume
413
Category
Article
ISSN
0005-2736

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## Abstract The ability of isoproterenol, glucagon, PGE~1~ and cholera toxin to stimulate the synthesis of cAMP and protein kinase activity in a line of liver cells (BRL) and a line of rat hepatoma cells (H35) has been determined. The concentration of cAMP in BRL cells (∼ 10 pmoles/mg protein) is