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Cholera toxin induced novel genes in human lymphocytes and monocytes

✍ Scribed by Atabak R. Royaee; Linda Jong; Chanaka Mendis; Rina Das; Marti Jett; David C.H. Yang


Book ID
116755686
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
150 KB
Volume
43
Category
Article
ISSN
0161-5890

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We investigated the action of cholera toxin on the intracellular ionized calcium [Ca2+]i increase induced by anti-CD2 and anti-CD3 monoclonal antibodies in the leukemic human T-cell line Jurkat. Cholera toxin inhibits in a dose-dependent manner these two pathways of human T-lymphocyte activation but