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Cholera toxin differentially regulates nitric oxide synthesis, tumor necrosis factor-α production and respiratory burst in murine macrophages

✍ Scribed by Boris L Rodrı́guez; Armando Rojas; Jorge A Benı́tez


Book ID
114304429
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
209 KB
Volume
22
Category
Article
ISSN
0928-8244

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Tumor necrosis factor-alpha is a principal mediator of the pathophysiological effects of endotoxemia and endotoxin shock. Tumor necrosis factor-a also contributes to the stimulation of nitric oxide synthesis by the induction of the enzyme nitric oxide synthase in a variety of tissues. Although the i