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Cholecystokinin octapeptide: Vesicular localization and calcium dependent release from rat brain in vitro

✍ Scribed by P.C. Emson; C.M. Lee; J.F. Rehfeld


Book ID
118940004
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
334 KB
Volume
26
Category
Article
ISSN
0024-3205

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## Abstract Nitric oxide (NO; 1 ΞΌM) or an NO donor (500 ΞΌM diethylenetriamine‐nitric oxide, DETA‐NONOate) caused rapid glutamate and ATP release from cultured rat cortical astrocytes. NO‐induced glutamate release was prevented by calcium chelators (EGTA or BAPTA‐AM) and an inhibitor of vesicular ex