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Cholecystokinin Effect on Human Lymphocyte Ionized Calcium and Mitogenesis

✍ Scribed by M.A. McMillen; A. Ferrara; T.E. Adrian; D.S. Margolis; H.C. Schaefer; K.A. Zucker

Book ID: 115634714
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 518 KB
Volume: 58
Category: Article
ISSN: 0022-4804
DOI: 10.1006/jsre.1995.1024

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## Abstract Elevated calcium and magnesium concentrations promoted mitotic activity in rat thymic lymphocyte cultures. Oestradiol inhibited calcium‐ but not magnesium‐induced mitogenesis. One prerequisite for the mitogenic action of calcium is a raised intracellular concentration of cyclic adenosin